Impact of disease state on arrhythmic event detection by action potential modelling in cardiac safety pharmacology
Dec 21, 2018 • By Bernard Christophe, William J. Crumb Jr.
Abstract Introduction The use of in silico cardiac action potential simulations is one of the pillars of the CiPA initiative (Comprehensive in vitro Proarrhythmia Assay) currently under evaluation designed to detect more accurately proarrhythmic liabilities of new drug candidate. In order to take…
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